Melocam
Composition
Tablets: Each tablet contains 7.5mg or 15mg Meloxicam.
Suppositories: Each suppository contains 15mg Meloxicam.
Ampoules: Each ampoule 2ml contains 15mg Meloxicam.
Properties
Melocam® (Meloxicam) is a non-steroidal anti-inflammatory belonging to the enolic acid group with potent anti-rheumatic effect and high tolerability as it is a preferential COX-2 inhibitor.
= Selective inhibition of COX-2 (cyclooxygenase-2) provides high anti-inflammatory, analgesic and anti-pyretic actions without gastro-intestinal or renal side effects as COX-2 is responsible for the production of prostaglandins at inflammatory sites while COX-1 is cytoprotective in the gastric mucosa and kidneys.
= Melocam® (Meloxicam) pharmacokinetic profile is characterized by a prolonged and almost complete absorption from the G.I.T.
= The elimination half-life is approximately 20 hours.
Indications
Rheumatic diseases especially for prolonged use e.g.:
- Osteoarthritis
- Rheumatoid arthritis
- Gouty arthritis
- Severe pain of any origin
Contra-Indictions
= Hypersensitivity to the drug
= Active peptic ulcer
= Severe hepatic insufficiency or non-dialyzed severe renal insufficiency
= Children under 15 years of age
= Pregnancy and lactation
Adverse Effects
Rarely, diarrhea, flatulence, constipation, nausea or abdominal pain may occur.